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The work by CCG members can be categorized into 4 main areas:

a) Synthesis and characterization of novel ligands and metal complexes.

b) Biological activities of the ligands and complexes.

  • Antimicrobial (antibacterial dan antifungal) activities
  • Antioxidant potential
  • DNA cleavage ability
  • Cytotoxicity on healthy cells

c) Corrosion inhibition properties of the ligands.

d) Catalytic activity of the complexes.


The synopsis of each area is as outlined below:

a) Novel Schiff base and hydroxamic acid ligands and their metal complexes

For academic curiosity and development of the field of fundamental research, ligands with new architecture and their various metal complexes are designed, synthesized and characterized in the laboratory.  The structural, physical and chemical data obtained from these novel compounds are useful in providing clues and guides for researchers interested to investigate the applications of these compounds in various fields.

b) Biological activity of ligands and metal complexes

Biological activity such as antibacterial, antifungal, antiviral, antioxidant, antitumour, antidiabetic and cytotoxicity can be investigated for the various compounds synthesized in as a small initial step itowards developing new drugs in combating the diseases that are compromising the quality of human life.

c) Corrosion inhibition potential of compounds containing heteroatoms and p-electron systems

Compounds that have anchoring points through lone pair of electrons and p-electrons can be designed and synthesized in an attempt to produce corrosion inbibitors for various metals such as mild steel, copper and zinc.  These compounds can be used as alternative to commercially available inorganic corrosion inhibitors which have the drawback of being toxic and harmful to human and the environment.

d) Catalytic properties of palladium and titanium Schiff base complexes

Novel homogeneous and heterogeneous catalytic system can be developed using the compounds synthesized in the laboratory to increase the efficiency, recoverability and ease of use of the catalyst for various chemical reactions such as Suzuki and Heck reactions of C-C cross coupling and oxidation reactions.  The heterogeneity is achieved by mounting the catalytic compounds on inert vehicles such as MCM-41 and carbon nanotubes (CNT).